I recently did a UCS C-series rackmount deployment. The servers came with a 10gbps 1225 VIC card and the core routers were a pair of 4500s in VSS mode.
The 1225 VIC card lets you carve virtual NICs from your physical NICs. You can put COS settings directly on the virtual NICS, enabling you to prioritize traffic directly on the physical NIC. For this deployment, I created 3 virtual NIC for each pNIC – Management, vMotion, and VM traffic. By setting COS to 6 for management, 5 for VMs, and 4 for vMotion on the vNICs, I ensure that management traffic is never interrupted, and I also guarantee that VM traffic will be prioritized over vMotion. This still allows me to take full advantage of 10gbps of bandwidth when the VMs are under light load.